甩尾測痛儀（疼痛甩尾測試儀甩尾儀Tail Flick Test Analgesia Meter Apparatus）（測試動物疼痛反應(yīng)時間和動物對鎮(zhèn)痛藥物的疼痛反應(yīng)極限使用簡便更多詳情敬請）
型號33型
疼痛甩尾測試儀用于測試動物疼痛反應(yīng)時間和動物對鎮(zhèn)痛藥物的疼痛反應(yīng)極限。實驗過程中檢測到動物尾部甩動后內(nèi)置的計時器自動停止計時。
The Tail Flick Test apparatus meter measures latency and/or temperature threshold when detecting properties of narcotic and strong non-narcotic drugs on mice and rats. A built-in Timer is automatically stopped when the animals’ tail flicks out of the beam of light, test result will be displayed on readout for viewing.
An overhead halogen light source is in a constant “ON” (idle state). A pre-focused heat source supplies an area of 4X6mm stimulation to the tail. A built-in sensor in the tail groove detects the tail flick of the animal. The tail groove is a non-metallic material to avoid unnecessary conditioning of your animals; unlike other systems. If the animal does not flick their tail within the pre programmed cut-off time; the heat source shuts off automatically; avoiding tissue damage. Built-in timer displays the reaction time in 0.01 second increments. Control of system can be from either the front panel or supplied footswitch: Start, Stop and Reset of tests.
疼痛甩尾測試儀主要特點
? 實時尾部溫度/觸發(fā)可選
? 觸發(fā)溫度設(shè)置功能
? 精確數(shù)字控制時間精確度為0.01秒
? 自動切斷保護功能
? 光束強度可調(diào)節(jié)步進量1％
? 自動檢測活動反應(yīng)
? 強制取消定時器功能
? 數(shù)字顯示功能
? 標(biāo)準計算機打印口輸出
? RS-232輸出
相關(guān)文獻
Gender-specific behavioral and immunological alterations in an animal?model?of autism induced by prenatal exposure to valproic acid
T Schneider, A Roman, A Basta-Kaim, M Kubera… - …, 2008 - Elsevier
… adverse developmental consequences produced by early brain injuries, especially in animal
models of human … valproic acid have not been studied in the presented animal model of autism …
withdrawal test carried out using an Analgesia Meter apparatus (Mod 33, IITC, INC, USA …
The antinociceptive effect of intrathecally administered adenosine analogs in mice correlates with the affinity for the A1-adenosine receptor
R Karlsten, C Post, I Hide, JW Daly - Neuroscience letters, 1991 - Elsevier
… The animals were used only once. Testing of tail flick was performed using an IITC Inc. Model
33 Analgesiameter, with the light focused on the tip of the tail [3]. The intensity of the beam was
adjusted to give a reaction time of 3-4 s before the it injection of the drug solutions …
Behavioral alterations in rats prenatally exposed to valproic acidanimal?model?of autism
T Schneider, R Przew?ocki - Neuropsychopharmacology, 2005 -
… The thermal paw withdrawal test was carried out using an Analgesia Meter apparatus (Mod 33,
IITC, Inc., USA) … aberrations described in this paper appear before puberty, which could distinguish the VPA rat model of autism from other animal models of psychiatric …
[PDF] Stress of chronic food restriction attenuates the development of adjuvant arthritis in male Long Evans rats
J Jurcovicova, M Stancikova, K Svik… - Clinical and …, 2001 - clinexprheumatol.org
… They had free access to food. In group four AA was induced and the animals received 60%
of the food consumed by the arthritic rats (group 3) on the previous day … The pain threshold
was measured using the tail flick analgesia meter (Model 33 IITC Inc …
Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice
Y Yajima, M Narita, M Narita, N Matsumoto, T Suzuki - Brain research, 2002 - Elsevier
… each of the hind paws of mice was tested individually using a thermal stimulus apparatus (model
33 Analgesia Meter; IITC Inc./Life Science … An aliquot of tissue sample was diluted with an equal volume of electrophoresis sample buffer (Protein Gel Loading Dye-2x …
[HTML] Prolonged gabapentin analgesia in an experimental mouse?model?of fibromyalgia
M Nishiyori, H Ueda - Molecular pain, 2008 -
… 10 μg in the neuropathic pain model, which is consistent with the previous study that … the ICS model is a promising candidate for experimental FMS or generalized pain syndrome models … thermal paw withdrawal test was carried out using a thermal stimulus (Model 33 Tail Flick …
Early neonatal experience of Long-Evans rats results in long-lasting changes in morphine tolerance and dependence
M Kalinichev, KW Easterling, SG Holtzman - Psychopharmacology, 2001 - Springer
… an organism's responsiveness to stress has been exten- sively investigated in several rodent
models … Previous findings by Kehoe and Blass (1986) provide indirect evidence indicating that
maternal … a light source was focused on the lower third of the tail (Model 33, Tail Flick …
Peripheral antinociceptive effects of MC4 receptor antagonists in a rat?model?of neuropathic pain–a chemical and behavioral study
K Starowicz, SA Mousa, I Obara, A Chocyk… - Pharmacological …, 2009 - Elsevier
… PWL) in response to noxious thermal stimuli using an Analgesia Meter (mod 33, IITC INC., Landing, NJ … The initial phase of the CCI model of neuropathic pain involves inflammation around the nerve …restricted to the dorsal horns of the spinal cord, similar to previous studies [26 …
Analgesia is produced by uterocervical mechanostimulation in ratsroles of afferent nerves and implications for analgesia of pregnancy and parturition
AR Gintzler, BR Komisaruk - Brain research, 1991 - Elsevier
… a lamp mounted 8 cm above the tail and was maintained until a response was elicited or 10 s
had elapsed (IITC Inc., Model 33, Landing, NJ) … Since in a previous study, there was no correlation between the magnitude of increase in TFL produced by vaginal stimulation and the …
An individual variation study of electroacupuncture analgesia in rats using microarray
YZ Gao, SY Guo, QZ Yin, T Hisamitsu… - The American journal of …, 2007 - World Scientific
… Previous studies have demonstrated that electroacupuncture (EA) at ST36 acupoint could produce profound analgesia … recording the tail flick latency (TFL) induced by radiant heat using Model 33 Tail Flick … Briefly, 750 ng of fast recovery sample cRNA were mixed with 750 ng of …
[PDF] Does exogenous melatonin influence the free radicals metabolism and pain sensation in rat
I Pekarkova, S Parara, V Holecek, P Stopka, L Trefil… - Physiol Res, 2001 - med.cas.cz
… It was found in our previous research in the field of pain that after repeated painful … The tail-flick test (TF) (Tail Flick Analgesia Meter Model 33, IITC Inc., Life Science Instruments, USA) measures the … Sample preparation On the last day of the experiment (the 5th day), after all the …
Direct evidence for the involvement of endogenous β-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state
K Niikura, M Narita, M Narita, A Nakamura, D Okutsu… - Neuroscience …, 2008 - Elsevier
… paws of rats were tested individually using a thermal stimulus apparatus (model 33 Analgesia
meter … In the present study, sample preparation was performed 10 days after partial sciatic … 2B).
Consistent with many previous studies which have characterized afferent projections to …
[PDF] Antinocieptive activity of Toddalia asiatica (L) Lam. in?models?of central and peripheral pain
HN Kariuki, TI Kanui, A Yenesew, NB Pa… - 2012 -
… Antinocieptive activity of Toddalia asiatica (L) Lam. in models of central and peripheral pain … Tail flick test A radiant heat tail-flick IITC Inc. Model 33 analgesiometer was used to measure response latencies according to the method described previously (Corrêa et al., 1996) …
